gave this one a bit of thought as well, and what would happen is, as the male body produced estrogen, his body would also transform his testosterone into estrogen, this way, if his body would put up a fight by producing more and more testosterone, it would be useless as it would then be converted into estrogen, which in turn could make his body produce the other female hormones, and once flooded with estrogen, there would be no turning back, a file like this would be for those who wish to become a shemale or wish to go thru M2F transition. in my mind, it would be better for the person if the hormones were natural rather than having to take synthetic hormones which could cause harmful effects or even death. a file such as this could be used rather than putting chemicals into the body.